Current view on hepatitis B diagnosis and therapy
نویسندگان
چکیده
Infekce virem hepatitidy B (HBV) je stĂĄle celosvÄtovÄ zdravotnĂm problĂŠm s mÄnĂcĂ se epidemiologiĂ v zĂĄvislosti na ĹadÄ faktorĹŻ, pĹedevĹĄĂm vakcinaÄnĂ politice a migraci. ChronickĂĄ infekce HBV dynamickĂ˝ proces, kterĂ˝ odråŞà interakce mezi virovou replikacĂ hostitelskou imunitnĂ odpovÄdĂ. Ne vĹĄichni pacienti chronicky infikovanĂ majĂ chronickou hepatitidu B. UkonÄenĂ lĂŠÄby nukleotidovĂ˝mi nebo nukleosidovĂ˝mi analogy (NA) zĂĄvaĹžnĂ˝m rozhodnutĂm, protoĹže spojeno nebezpeÄĂm reaktivace mnoĹženĂ viru, kterĂŠ projevĂ vzestupem hladiny DNA, aktivity ALT zĂĄnÄtlivĂŠ jaternĂ histologii. NejbezpeÄnÄjĹĄĂ ukonÄit lĂŠÄbu aĹž po vymizenĂ HBsAg, coĹž parametr dosaĹženĂ kontroly nad infekcĂ HBV.
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ژورنال
عنوان ژورنال: Vnitr?ni? le?kar?stvi?
سال: 2021
ISSN: ['0042-773X', '1801-7592']
DOI: https://doi.org/10.36290/vnl.2021.007